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Security
Companies that store data internally, on-premises, have complete control over it in terms of accessibility (read) and maintenance (insert, update, delete) rights. But great power comes with great responsibility. IT departments are responsible to guarantee the appropriate privacy and respect their own, local, and legal rules. In Europe, the recent General Data Protection Regulation (GDPR) defines clearly how to rank and handle it. This is a cost for all companies that are requested today to implement, maintain and monitor those rules in all business processes.
The same applies to the hosting environment: if you are delivering a hosting service, then you have to update your business process and enpower your staff to cope with security and legally guarantee the security level requested, at least, by the current laws in your country. If you are the CEO, CFO, or IT manager of a company that uses outsourced hosting services for your ERP, then you have probably signed an SLA where your hosting provider guarantees the security of your own data. The cost of the service is higher according to the level of security.
There are no companies in the world that can guarantee the highest service SLA guaranteed by Microsoft Cloud security policies offered with Microsoft Dynamics 365 Business Central. Being a cloud service (always up to date), it is already compliant with all the regulations of the countries where it is deployed, included in the GDPR. There is no extra cost to pay.